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From the Townsend Letter
April 2019

The Whole-Body Approach to Treating Allergies
by Clement Lee, NMD
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For the blood and lymph, we encourage adequate exercise two to three times per week of at least 15 minutes. Simple things like jumping rope or using a rebounder can stimulate lymphatic movement. Additionally, hydrotherapy techniques such as alternating cold/hot water baths can help stimulate circulation. These same therapies help with skin and lung function.
     
For skin elimination, we suggest sweating through exercise, infrared sauna usage, dry brushing. Sweating is helpful for eliminating toxins, as the skin is the largest organ in the body.22
     
For lung function, practice deep breathing, or exercise, which can also help lower stress.23 Look to getting a high-quality air filtration system for home and/or work use to minimize toxic air exposure.
     
For kidneys, the simple place to start is with adequate hydration. Aim to drink one-half of the body weight in ounces of filtered water to support adequate hydration. For example, if a patient weighs 160 pounds, they should aim for 80 ounces of water per day. There is some variability to this calculation, but it is a helpful rule of thumb.
     
For the GI system, focus on proper elimination and microbiome balance. Ensure patients have a minimum of one bowel movement per day. Adequate hydration can help with constipation.24 Address microbiome balance with prebiotic fiber, probiotics, or antimicrobials if necessary. By changing the diet and limiting processed foods, it can help favorably alter the microbiome.25
     
There are a lot of steps for optimizing the emptying of this “bucket,” but what I've found most helpful for patients are the pre-packaged-detoxification programs by several nutraceutical companies. I typically use kits like Designs for Health 14-day Paleo-cleanse and Thorne Mediclear 10-day program. They make it easier for the patient by supplying adequate amounts of micronutrients, herbs, and amino acids to support the majority of the biochemistry of detoxification. In addition, they serve as one-to-two meal replacements so patients will have less struggle with deciding which food options to choose from. Patients only need to focus on one major meal of the day, which will improve their compliance with the recommendations. There are similar programs and kits offered by other nutraceutical companies. The advantage to these programs is that they give patients a tangible and simplified process to start on while they get used to making the lifestyle changes.

Research NutritionalsSymptom-Relief Treatment Options
There are currently a wide range of treatment options available that I use in practice to help treat allergy symptoms. They range from temporary relief to more permanent lasting solutions. I will give examples of these options.
     
Nutrition. As mentioned above, start with foundational nutrition like a quality multivitamin.
Nettle leaf (Urtica dioica) has shown benefit for people suffering from allergic rhinitis.26 Silymarin, a common herb used for liver support, has also shown benefit for alleviating the severity of allergic rhinitis symptoms.27 Vitamins A, C, and E have shown some protective benefit on airway symptoms and may reduce wheezing symptoms.28,29 Omega 3 oils from fatty fish show protection for childhood asthma risk and reducing atopic dermatitis.30,31 There are supplements that have a combination of the above ingredients that we use in practice to give patients allergy symptom relief.
     
Quick relief. A newer supplement product containing an enzyme known as diamine oxidase (DAO) has been shown to give rapid symptom relief for allergic reactions. DAO helps to break down histamine in the body. Elevated histamine can lead to gastrointestinal upset, migraine, irritation of nasal mucosa, itching, or other forms of allergy. DAO, along with other enzymes, has the potential to break down and excrete histamine quickly thus helping to reduce the symptoms of allergy and food intolerance.32,33 The only downside is that currently the products on the market are relatively expensive when compared to other supplements. This should be used as temporary support while helping to address the underlying causes.
     
Nasal sinus relief. Nasal symptoms seem to be the most common presentation of allergies. Chronic runny nose or recurrent sinus infections are common conditions we see. Simple solutions, such as saline nasal rinse, can be helpful for chronic rhinosinusitis.34 For tougher cases, addressing the underlying causes is helpful at eliminating chronic rhinitis. Some of the underlying causes could be naso-sinus fungal, polymicrobial, or multidrug resistant bacteria biofilm. This could be caused by mold exposure through water-damaged buildings or frequent use of antibiotics.35,36 Either way there are helpful agents that can be used for treatment and improvement of symptoms. Colloidal silver nasal spray has been shown to be effective against the biofilm activity and may be more superior than oral antibiotics.36 Other agents such as N-acetyl cysteine and EDTA may assist in the biofilm disruption and enhance the effect of antifungal and antimicrobials.37
     
Treating the gut. Healthy micro-biome balance is important. Proper prebiotics and probiotics have an effect on allergy development.38 Specific probiotics like Saccharomyces cerevisiae and Lactobacillus rhamnosus have shown to reduce allergic rhinitis and nasal congestion and reduce food allergy.39,40 Spore forming bacilli of the Bacillus species are showing promise for the treatment of gut dysbiosis, diarrhea, IBS, obesity, type 2 diabetes, cardiovascular conditions, and more.41 In our practice, we use the product Mega Sporebiotic, which has shown benefit in patients dealing with inflammation and allergy symptoms.
     
Parasitic infection. An often-overlooked source of underlying allergy symptoms are parasitic infections. Various protozoa and parasites such as Plasmodium falciparum, Dientamoeba fragilis, Blastocystis, Cryptosporidium spp., Entamoeba histolytica, Entamoeba dispar, and Giardia intestinalis can lead to symptoms of asthma, atopic dermatitis, food allergy/intolerance, mast cell activation, anaphylaxis, and other inflammatory conditions.42-45 One of the most effective treatments for parasites I have seen in my practice is the use of nitazoxanide (Alinia). It has been shown effective for a wide variety of parasites, helminths, in addition to H. pylori, Campylobacter jejuni, and potentially Clostridium difficile, Rotavirus and other viruses.46-48 It has an extremely low side effect profile. For those without infections, the medication effects are comparable to placebo. I use a higher than normal prescribed dose of 1 g BID for up to 15 days. Patients generally tolerate the treatment well. There are times when I need to start at a smaller dose 250 mg BID for the first few days depending on the initial effects of the drug. Common adverse effects are temporary increase in gastrointestinal effects, primarily diarrhea or abdominal discomfort. Rarer effects are temporary yellowing of the skin and eyes that clear up when discontinuing the medication. I have had success in clearing chronic eczema cases in which the previously mentioned treatments have failed.
     
Allergy ResearchAllergy Tolerance. One last treatment option I use in my practice has shown rapid and effective resolution of chronic and acute allergy symptoms, especially hay fever. Low dose allergy therapy (LDA) has been discussed in previous articles.49 For patients dealing with simpler cases of seasonal allergies, one to two treatments of LDA were able to get a virtual elimination or significant reduction in their allergy symptoms. I typically use this therapy as a supportive treatment for building allergy tolerance. I have seen patients have significant reduction in food intolerances following this therapy. It is typically recommended for patients to have the LDA treatment once every two months for six to eight treatments.

Summary
Allergies can be treated effectively by addressing the whole person and their individual underlying conditions. Most patients can benefit with general detoxification support to help lower their total body burden. However, personalized treatment approaches can yield far superior results to eliminate allergy symptoms.

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References .pdf

Financial Disclosures:
I have not been paid nor have any financial interest in the products and services mentioned in the article.

Clement Lee, NMDClement Lee, NMD, received a BS in biological sciences from University of California, Irvine, and Doctorate of Naturopathic Medicine from Southwest College of Naturopathic Medicine. Dr. Lee is the founder of Optimal Health & Wellness in Pasadena, California, a clinic that uses cutting edge integrative and holistic therapies to support patients with chronic illness and others to gain general wellness, or optimal health. Dr. Lee has extensive training on regenerative medicine and injection therapies, anti-aging, IV therapies, environmental medicine, and functional medicine. Dr. Lee sees patients dealing with wide variety of gastrointestinal issues, allergies, chronic infections, autoimmunity, chronic pain and injuries, disease of aging, and more. More information on Dr. Lee's practice can be found at www.opthealthwellness.com.

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