Townsend Letter Alternative Medicine Magazine

 

 

  FREE e-Edition

 

 EDTA Chelation Therapy

 

 E-mail List

 

 TLDP.com


From the Townsend Letter
August/September 2015

Acidity Kills the Pancreas
by Peter Melamed, PhD, and Felix Melamed, MS
Search this site

Page 1, 2, 3

Notes
1.      Melamed P, Melamed F. Healthy Pancreas, Healthy You. 2012. Available at https://www.smashwords.com/profile/view/healthypancreas.
2.      Boron WF.
Medical Physiology: A Cellular and Molecular Approach. Elsevier/Saunders; 2003:1300.
3.      McCance K, Huether S.
Pathophysiology: the Biologic Basis for Diseases in Adults and Children. 2nd ed. Mosby; 1994.
4.      Saunders JH, Wormsley KG. Pancreatic extracts in the treatment of pancreatic exocrine insufficiency.
Gut. 1975;16:157–162.
5.      Case RM, Scratcherd T, D'A Wynne R. The origin and secretion of pancreatic juice bicarbonate.
J Physiol. (London) 1970;210:1.
6.      Ball EO, Tucker HF, Solomon AK, Vennesland B. The source of pancreatic juice bicarbonate.
J. Biol. Chem.1941;140:119.
7.      Matsuno S, Sasaki Y, Kobari M, et al. Initial pathophysiological changes in chronic pancreatitis induced by pancreatic ductular obstruction model.
Tohoku J. Exp. Med.1991;163(3):199–210.
8.      McClave SA. Feeding the chronically ill patient [audio recording]. Audio-Digest Gastroenterology. 42nd Annual Gastroenterology Update. Cleveland Clinic, Department of Gastroenterology and Hepatology. November 2006.
9.      Johnson LR, Byrne JH.
Essential Medical Physiology. 3rd ed. Academic Press; 2003.
10.    Talamini G. Duodenal acidity may increase the risk of pancreatic cancer in the course of chronic pancreatitis: an etiopathogenetic hypothesis
JOP. 2005;6(2):122–127.
11.    Case RM, Harper AA, Scratcherd T. The secretion of electrolytes and enzymes by the pancreas of the anaesthetized cat.
J Physiol. 1969;201:335–348.
12.    Baron JH. The pancreas.
Mt Sinai J Med. January 2000;67(1):68–75.
13.    Scratcherd T. Case RM. The secretion of electrolytes by the pancreas.
Am J Clin Nutr. Mar 1973;26:326–339.
14.    Whitcomb DC. Advances in understanding the mechanisms leading to chronic pancreatitis.
Nat Clin Pract Gastroenterol Hepatol. 2004 Nov;1(1):46–52.
15.    Bennett WS, Huber R. Structural and functional aspects of domain motions in proteins. CRC
Crit Rev Biochem. 1984;15:291–384.
16.    Green NM, Work E. Pancreatic trypsin inhibitor. 2. reaction with trypsin.
Biochem J. 1953 May; 54(2):347–352.
17.    Niederau C, Grendell JH. Intracellular vacuoles in experimental acute pancreatitis in rats and mice are an acidified compartment.
J Clin Invest. 1988;81(1):229–236.
18.    Bhoomagoud M, Jung T, Atladottir J, et al. Reducing extracellular pH sensitizes the acinar cell to secretagogue-induced pancreatitis responses in rats.
Gastroenterology. 2009 September;137(3):1083–1092.
19.    Myneni N, Minocha A. Bile acids and esophageal injury: a resolution to the controversy?
Am J Gastroenterol. 1999 Dec;94(12):3649–3650.
20.    Cronin J, Williams L, McAdam E, et al. The role of secondary bile acids in neoplastic development in the oesophagus.
Biochem Soc Trans. 2010 Apr;38(2):337–342.
21.    Penagini R. Bile reflux and oesophagitis.
Eur J Gastroenterol Hepatol. 2001 Jan;13(1):1–3.
22.    Rege RV, Moore EW. Pathogenesis of calcium-containing gallstones. Canine ductular bile, but not gallbladder bile, is supersaturated with calcium carbonate.
J Clin Invest. 1986;77(1):21–26.
23.    Rubinstein E, Mark Z, Haspel J, et al. Antibacterial activity of the pancreatic fluid.
Gastroenterology. 1985 Apr; 88(4):927–932.
24.    Pierzynowski SG, Zabielski R.
Biology of the Pancreas in Growing Animals. Elsevier; 1999:131.
25.    Frassetto L, Morris RC, Todd K, Sebastian A. Chronic low-grade metabolic acidosis in normal adult humans: pathophysiology and consequences. Medical Science Symposia Series.
Women's Health and Menopause. 1999;13:15–23.
26.    Morris RC, Schmidlin O, Frassetto LA, Sebastian A. Relationship and Interaction between Sodium and Potassium.
J Am Coll Nutr. 2006;25(90003):262–270.
27.    Frassetto L, Morris R.C, Sebastian A. Potassium bicarbonate reduces urinary nitrogen excretion in postmenopausal women.
J Clin Endocrinol Metab. 1997;82(1):254–259.
28.    Sebastian A, Frassetto LA, Sellmeyer DE, Merriam RL, Morris RC. Estimation of the net acid load of the diet of ancestral preagricultural Homo sapiens and their hominid ancestors.
Am J Clin Nutr. 2002;76(6):1308–1316.
29.    Sebastian A, Harris ST, Ottaway JH, Todd KM, Morris RC. Improved mineral balance and skeletal metabolism in postmenopausal women treated with potassium bicarbonate.
N Engl J Med. 1994 Jun 23;330(25):1776–1781.
30.    Frassetto L, Sebastian A. Age and systemic acid-base equilibrium: analysis of published data.
J Gerontol. 1996;51:91–99.
31.    Frassetto L, Morris Jr RC, Sebastian A. Effect of age on blood acid-base composition in adult humans: role of age-related renal functional decline.
Am J Physiol. 1996;271:1114–1122.
32.    Benda J. Karlovarsky Mlynsky Pramen. Domaci pitna lecba. DTP-servis mariuuskelazue. 1997.
33.    Solc P. Karlovarska lazenska leba a medicina na prelomu 20. A21. Stoleti. Galen, Praha; 2000.
34.    Lesniak RJ, Hohenwalter MD, Taylor AJ. Spectrum of causes of pancreatic calcifications.
Am J Roentgenol. January 2002;178(1). http://www.ajronline.org/content/178/1/79.full.
35.    Raeder M, Mo A, Aune S. Effect of plasma H+-ion concentration on pancreatic HCO-3 secretion.
Acta Physiologica Scandinavica. 2008;105(4):420–427.
36.    Introduction to Enzymes. In: Worthington Enzyme Manual [online document]. Worthington Biochemical Corporation. 2010. http://www.worthington-biochem.com/introbiochem/default.html.
37.    Hegyi P, Maleth J, Venglovecz V, Rakonczay Z. Pancreatic Ductal Bicarbonate Secretion: Challenge of the Acinar Acid Load.
Front Physiol. 2011;2:36.PMID: 21808623.
38.    Fluhr G et al. Pre-study protocol MagPEP: a multicentre randomized controlled trial of magnesium sulfate in the prevention of post-ERCP pancreatitis.
BMC Gastroenterology 2013;13:11.
39.    Robey IF. Examining the relationship between diet-induced acidosis and cancer.
Nutr Metab. 2012;9:72.
40.    Fass R. Approach to refractory gastroesophageal reflux disease in adults. UpToDate. Waltham, MA; 2015. http://www.uptodate.com/contents/approach-to-refractory-gastroesophageal-reflux-disease-in-adults
41.    Worning H. Exocrine pancreatic function in dyspepsia.
Digestion 1987;37(Suppl. 1):3–13.
42.    Demir K. Pancreatic dyspepsia: a place for pancreatic insufficiency in dyspepsia.
J Surg Sci. 2012;3(1):1–4.
43.    Kumar K,  Ghoshal UC, et al. Small intestinal bacterial overgrowth is common both among patients with  alcoholic and idiopathic chronic pancreatitis.
Pancreatology. 2014 Jul–Aug;14(4):280–283. Epub 2014 May 27.
44.    Leeds JS, Hopper AD, et al. Some patients with irritable bowel syndrome may have exocrine pancreatic insufficiency.
Clin Gastroenterol Hepatol. 2010 May;8(5):433–8. doi: 10.1016/j.cgh.2009.09.032. Epub 2009 Oct 14.
45.    Goepp J, Fowler E, McBride T, Landis D. Frequency of abnormal fecal biomarkers in irritable bowel syndrome.
Glob Adv Health Med. 2014 May;3(3):9–15. doi:10.7453/gahmj.2013.099.
46.    Money ME, Hofmann AF, et al. Treatment of irritable bowel syndrome-diarrhea with pancrealipase or colesevelam and association with steatorrhea.
Pancreas. 2009;38(2):232–233.
47.    Scott GN. Can pancreatic enzymes be used to treat indigestion?
Medscape. Mar 05, 2014.
48.    Smith RC, Talley NJ, Dent OF, et al. Exocrine pancreatic function and chronic unexplained dyspepsia. A case-control study.
Int J Pancreatol. 1991;8:253–262.
49.    Mahadeva S, Goh KL. Epidemiology of functional dyspepsia: a global perspective.
World J Gastroenterol. 2006;12(17):2661–2666.
50.    Okada R, Okada A, Okada T, et al. Elevated serum lipase levels in patients with dyspepsia of unknown cause in general practice.
Med Princ Pract. 2009;18:130–136.
51.    Lindström E, Schenck H, Ihse I. Pancreatic exocrine and endocrine function in patients with pancreas divisum and abdominal pain.
Int J Pancreatol. 1990 Jan;6(1):17–24.
52.    Ashizawa N, Hashimoto T, Miyake T, et al. Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective?
J Gastroenterol Hepatol. 2005;21(4):767–771.
53.    Andren-Sandberg A, Hardt PD. Second Giessen International Workshop on Interactions of Exocrine and Endocrine Pancreatic Diseases.
J Pancreas. 2008;9(4):541–575.

Peter Melamed, PhD, and Felix Melamed, MS, are licensed practitioners from Biotherapy Clinic of San Francisco. They are authors of the many articles on Internet, the book Natural European Way of Whole Body Cleansing, and the eBook Healthy Pancreas, Healthy You that consists of three interrelated parts:
  I. Structure, Function and Disorders of the Pancreas
II. Healing Food in the Digestive (Pancreatic) and Metabolic Disorders
III. How to Improve the Exocrine Pancreatic Function, Postpone Pancreatic Deterioration, and
     Heal Digestive (Pancreatic) Disorders

In 1975, Peter Melamed established Biotherapy as a natural, holistic approach to healing. Biotherapy combines the wisdom of traditional Russian folk medicine, ancient Oriental medical therapies, and European naturopathy with cutting-edge Western technology. Biotherapy Clinic of San Francisco specializes in nondrug healing digestive (pancreatic), liver, gallbladder, and metabolic disorders.

Page 1, 2, 3

Consult your doctor before using any of the treatments found within this site.

Subscriptions are available for Townsend Letter, the Examiner of Alternative Medicine
magazine, which is published 10 times each year. Search our pre-2001 archives for further information. Older issues of the printed magazine are also indexed for your convenience.
1983-2001 indices ; recent indices. Once you find the magazines you'd like to order, please
use our convenient form, e-mail subscriptions@townsendletter.com, or call 360.385.6021.

 

360.385.6021
Fax: 360.385.0699
info@townsendletter.com

Who are we? | New articles | Featured topics | e-Edition |
Tables of contents
| Subscriptions | Contact us | Links | Classifieds | Advertise |
Alternative Medicine Conference Calendar | Search site | Archives |
EDTA Chelation Therapy | Home

© 1983-2015 Townsend Letter
All rights reserved.
Website by Sandy Hershelman Designs