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From the Townsend Letter
December 2013

Efficacy of Benfotiamine in the Management of Glycation
by Gaetano Morello, ND
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1.   Goldberg T, Cai W, Peppa M. Advanced glycoxidation end products in commonly consumed foods. J Am Diet Assoc. 2004 Aug;104(8):1287–1291.
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8.   Lin J, Alt A, Liersch J, Bretzel RG, Brownlee M, Hammes H-P. Benfotiamine inhibits intracellular formation of advanced glycation end products in vivo. Available at: Accessed April 27, 2013.
9.   Stirban A, Negrean M, Stratmann B, et al. Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes Care. 2006;29(9):2064–2071.
10. Stirban A, Negrean M, Stratmann B, et al. Adiponectin decreases postprandially following a heat-processed meal in individuals with type 2 diabetes: an effect prevented by benfotiamine and cooking method. Diabetes Care. 2007;30(10):2514–2516.
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14. Geohas J, Daly A, Juturu V, Finch M, Komorowski JR. Chromium picolinate and biotin combination reduces atherogenic index of plasma in patients with type 2 diabetes mellitus: a placebo-controlled, double-blinded, randomized clinical trial. Am J Med Sci. 2007 Mar;333(3):145–153.
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18. Rashid I, van Reyk DM, Davies MJ. Carnosine and its constituents inhibit glycation of low-density lipoproteins that promotes foam cell formation in vitro. FEBS Lett. 2007 Mar 6;581(5):1067–1070.
19. Alhamdani MS, Al-Azzawie HF, Abbas FK. Decreased formation of advanced glycation end-products in peritoneal fluid by carnosine and related peptides. Perit Dial Int. 2007 Jan–Feb;27(1):86–89.
20. Gugliucci A, Kotani K, Taing J, et al. Short-term low calorie diet intervention reduces serum advanced glycation end products in healthy overweight or obese adults. Ann Nutr Metab. 2009;54(3):197–201.
21. Uribarri J, Woodruff S, Goodman S, et al. Advanced glycation end products in foods and a practical guide to their reduction in the diet. J Am Diet Assoc. 2010 Jun;110(6):911–916.
22. Boor P, Celec P, Behuliak M, Grancic P, et al. Regular moderate exercise reduces advanced glycation and ameliorates early diabetic nephropathy in obese Zucker rats. Metabolism. 2009 Nov;58(11):1669–1677.

Dr. Gaetano MorelloDr. Gaetano Morello is a naturopathic physician practicing in West Vancouver, Canada. He received his bachelor of science degree from the University of British Columbia and his doctor of naturopathic medicine from Bastyr University of Natural Health Sciences in Seattle, Washington. Since 1991, Dr. Morello has been training and educating physicians, pharmacists, and health experts on the scientific use of natural medicines in the fields of cardiology, immunology, gastroenterology, anti-aging, and detoxification. Contributing author to the authoritative text on Alternative Medicine, A Textbook of Natural Medicine, he is also author of The Fiber Miracle. Lecturer and regular contributor to a number of magazines, journals, and publications, Dr. Morello has hosted and appeared on numerous television and radio shows discussing the power of natural medicine. In 2013, Dr. Morello joined the newly created Complex Chronic Disease Program located at BC Women's Hospital & Health Centre.

His publications include The Cleanse, Ultimate Inside Out Approach, Whole Body Cleansing, Transform your Health, Fiber Wonder, and Probiotic Breakthrough, and a contribution to A Textbook of Natural Medicine. Dr. Morello has also written hundreds of articles.

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