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From the Townsend Letter
July 2013

Rethink Health: Inflammation Is Actually Repair Deficit: Using Physiology First to Achieve Better Outcomes
Part 2: The Alkaline Way is a Synthesis of Synergistic Healthful Habits
by Russell Jaffe, MD, PhD, CCN, and Jayashree Mani, MS, CCN
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Drs. Robert Corish, Carl Franzblau, Norm Schwartz, and Brian McGuckin are acknowledged for their helpful critiques of this writing.

Resources
LRA by ELISA/ACT tests are
available from:
ELISA/ACT Biotechnologies
109 Carpenter Dr., Suite 100
Sterling, Virginia 20164
800-553-5472
ClientServices@ELISAACT.com
www.ELISAACT.com

Nutritional supplements mentioned in this article are available from:
PERQUE Integrative Health
44621 Guilford Drive, Suite 150
Ashburn, Virginia 20147
800-525-7372
Clientservices2@PERQUE.com
www.PERQUE.com

For functional biomarker tests:
Better Lab Tests Now
clientservices@BetterLabTestsNow.com
www.BetterLabTestsNow.com
http://betterlabtestsnow.com/predictive-bio-markers-panel.aspx

ZRT Lab
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Notes

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35. Gonick HC, Goldberg G, Mulcare D. Reexamination of the acid-ash content of several diets. Am J Clin Nutr.1968;(21):898–903.
36. Brown SE, Trivieri L Jr. The Acid Alkaline Food Guide: A Quick Reference to Foods & Their Effect on pH Levels. Garden City Park, NY: Square One Publishers; 2006.
37. Tzanavari T, Giannogonas P, Karalis KP. TNF-alpha and Obesity. Curr Dir Autoimmun. 2010; 11:145–156.
38. Johnson R. The Fat Switch. Amazon Digital Services; 2012.
39. Simopolous A et al. Bellagio Report on Healthy Agriculture Healthy Nutrition Healthy People, Center for Nutrition, Nutrigenomics, and Nutrigenetics. Washington, D.C.; 2013.
40. Seifter JL. Acid-base disorders. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia: Saunders Elsevier; 2011.
41. Jaffe R. Immune defense and repair systems in biologic medicine: clinical relevance of biological response modifiers in autoimmunity: diagnosis, treatment, tests and interpretation. Part II. Townsend Lett. 2009;316:90–98.
42. Jaffe R, Mani J, DeVane J, Mani H. Tolerance loss in diabetics: Association with foreign antigen exposure. Diabet Med., 2006;23(8):924–925.
43. Webinar on metabolic acidosis featuring Siggaard Anderson nomogram.
44. Jaffe R, Brown S. Acid-alkaline balance and its effect on bone health. Intl J Integrative Med. 2000;2(6):7–18.
45. Machha A, Achike FI, Mustafa AM, Mustafa MR. Quercetin, a flavonoid antioxidant, modulates endothelium-derived nitric oxide bioavailability in diabetic rat aortas. Nitric Oxide. 2007 Jun;16(4):442–447.
46. www.PERQUE.com/Polyphenolics. (Editor's note: Bad link.)
47. PERQUE Whey Guard Repair [website]. http://perquewheyguardrepair.com.
48. PERQUE Potent C Guard Powder [website]. http://www.perque.com/?s=potent+c+guard.
49. Middleton E et al. The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease and cancer. Pharmacol Rev. 2000;52:673–751.
50. Chew BP, Park JS. Carotenoid action on the immune response. J Nutr. 2004 Jan;134(1):257S–261S.
51. Shute EV. Proposed study of vitamin E therapy. Can Med Assoc J. 1972 May. 20;106(10):1057.
52. Heaney RP. Vitamin D in health and disease. Clin J Am Soc Nephrol. 2008 Sep;3(5):1535–1541.
53. Schrauzer GN.. Selenomethionine: A review of its nutritional significance, metabolism and toxicity. J Nutr. 2000;130:1653–1656. http://jn.nutrition.org/content/130/7/1653.full - FN1.
54. Jones OA, Maguire ML, Griffin JL. Environmental pollution and diabetes: a neglected association. Lancet. 2008 Jan 26;371(9609):287–288.
55. Navas-Acien A, Silbergeld EK, Pastor-Barriuso R, Guallar E. Arsenic exposure and prevalence of type 2 diabetes in US adults. JAMA. 2008 Aug 20;300(7):814–822.
56. Biodetox webinar.
57. Lee BJ, Huang YC, Chen SJ, Lin PT. Effects of coenzyme Q10 supplementation on inflammatory markers (high-sensitivity C-reactive protein, interleukin-6, and homocysteine) in patients with coronary artery disease. Nutrition. 2012 Feb 16.
58. Swanson D, Block R, Mousa SA. Omega-3 fatty acids EPA and DHA: health benefits throughout life. Adv Nutr. 2012 Jan;3(1):1–7.
59. St-Onge MP, Jones PJ. Physiological effects of medium-chain triglycerides: potential agents in the prevention of obesity. J Nutr 2002; 132(3):329–332.
60. Wutzke KD, Lorenz H. The effect of l-carnitine on fat oxidation, protein turnover, and body composition in slightly overweight subjects. Metabolism. 2004 Aug;53(8):1002–1006.
61. Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S. Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. JAMA. 1999 May 12; 281(18):1722–1727.
62. Munhoz CD, García-Bueno B, Madrigal JL, Lepsch LB, Scavone C, Leza JC. Stress-induced neuroinflammation: mechanisms and new pharmacological targets. Braz J Med Biol Res. 2008 Dec;41(12):1037–1046. Review.
63. Mishra R. The Textbook of Yoga Psychology: The Definitive Translation and Interpretation of Patanjali's Yoga Sütras for Meaningful Application in All Modern Psychologic Disciplines. Julian Press; 1987.
64. Seligman M. Learned Optimism: How to Change Your Mind and Your Life. Free Press; 1998.
65. Ohio State University. Massaging muscles facilitates recovery after exercise. Science Daily. 12 Aug 2008. Epub 26 Mar 2012.
66. Whiting SJ, Bell J. First morning urine measured with pH paper strips reflects acid excretion, presented at 2002 ASBMR American Society for Bone and Mineral Research.
67. Lehninger AL, Nelson DL, Cox MM, eds. Lehninger Principles of Biochemistry. 4th ed. WH Freeman and Company; 2005.
68. Health Studies Collegium. The Joy of Food: The Alkaline Way Guide. 18th ed. 2009–2010.
69. Galen RS, Gambino SR. Beyond Normality. Churchill Livingstone; 1976.
70. Alberts B, Johnson A, Lewis J, Raff M, Roberts K, Walters P. Molecular Biology of the Cell  4th ed. New York and London: Garland Science; 2002. http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowTOC&rid=mboc4.TOC&depth=2.
71. Janeway CA Jr, Travers P, Walport M. Immunobiology: The Immune System in Health and Disease. 6th ed. Garland Science; 2005.
72. Jaffe R, Mani J, DeVane J, Mani H. Tolerance loss in diabetics: Association with foreign antigen exposure. Diabet Med. 2006;23(8):924–925.

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