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From the Townsend Letter
June 2019

Postbiotic Metabolites:
The New Frontier in Microbiome Science

by Ross Pelton, RPh, PhD, CCN
Scientific Director, Essential Formulas
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Many gastrointestinal problems can be improved and/or resolved by increasing the quantity and the diversity of postbiotic metabolites in the microbiome. One method involves two actions:
a.   Adopt a healthy plant-based, fiber-rich diet. The dietary fibers will "feed" your beneficial probiotic bacteria which will enable them to grow and proliferate.
b.   Eliminate the high fat, high sugar, processed foods that alter the microbiome ecosystem and promote the proliferation of pathological bacteria.
However, if your microbiome is unbalanced, it is important to realize that consuming high-fiber foods doesn't guarantee fast results because you have a deficiency of probiotic bacteria present. It takes time for your reduced population of beneficial bacteria to process dietary fiber and create postbiotic metabolites, which will begin to shift the microbiome ecosystem back to a healthy state.

A much faster method of resolving intestinal problems is to ingest post-biotic metabolites directly. As men-tioned previously, each dose of Dr. Ohhira's Probiotics delivers over 400 postbiotic metabolites. Thus, Dr. Ohhora's Probiotics deliver a balanced microbiome formula that contains probiotics, prebiotics and most importantly, a multitude of postbiotic metabolites. This is why Dr. Ohhira's Probiotics work fast and effectively to improve many intestinal problems. This is the Dr. Ohhira's Difference!
I want to make an analogy between NASA's mission control center, which regulates our space flights and your microbiome. Many scientists and engineers work in NASA's mission control center. However, it is the hundreds of computers making millions of computations per second that control our space flights. The scientists and engineers are critically important, and the system wouldn't work or even exist without them. However, it is the computers that are the master regulators of space flights.
Similarly, your probiotic bacteria are critically important for the functioning of your microbiome ecosystem. However, it is the multitude of postbiotic metabolites that are the "mission control center" that send millions of biochemical signals, which influence every organ system. Postbiotic metabolites are the master health-regulating compounds in the body. This is why postbiotic metabolites are the new frontier of microbiome science.
In closing, I want to emphasize that the most critical factor in creating and maintaining a healthy microbiome is a healthy plant-based, fiber-rich diet. If you don't feed your probiotic bacteria well, they won't thrive and survive. When people consume high sugar, high fat, processed foods, they promote the growth of pathological bacteria that can cause many health problems. Remember, when you eat, you are not just eating for yourself, you are feeding 100 trillion guests. This is why a healthy diet is the most significant factor for a healthy microbiome and a healthy life.

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References .pdf

Ross Pelton, RPh, PhD, CCNRoss Pelton is the Natural Pharmacist. He received his BS degree in pharmacy from the University of Wisconsin. He also has a PhD in psychology and is a certified clinical nutritionist (CCN). In October 1999, Ross was named as one of the Top 50 Most Influential Pharmacists in America by American Druggist magazine for his work in natural medicine. He is the author of ten books and numerous online health seminars. Ross is currently the scientific director for Essential Formulas. The link to his blog and personal website is

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