The following excerpt is from The LDN Book, Volume 2: The Latest Research on How Low Dose Naltrexone Could Revolutionize Treatment for PTSD, PAIN, IBD, Lyme Disease, Dermatologic Conditions, and More (Chelsea Green Publishing, October 2020), edited by Linda Elsegood and is reprinted with permission from the publisher.
There are several gastrointestinal (GI) diseases and disorders for which low dose naltrexone has been applied as a therapeutic agent. The pathological factors that allow for the use of LDN in gut disorders and diseases include uncontrolled inflammation, abnormal immunity, increased intestinal permeability, increased visceral hypersensitivity, abnormal motility, and unregulated cellular growth.









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