Widespread Use of Medications That Cause Weight Gain
A survey of 11,055 US adults participating in the National Health and Nutrition Examination Survey (NHANES) from 2013 to 2016 revealed that 23% had taken at least one drug during the previous 30 days that has obesity as a side effect. Drugs that are considered obesogenic include all glucocorticoids, beta-blockers, and antihistamines; and some antidepressants, antipsychotic agents, antidiabetic medications, and progestin-only oral contraceptives. The use of these drugs was more common among people who were obese than among those who were not obese. The author of this report suggested that the association may be “bidirectional,” in that increasing use of obesogenic drugs may contribute to obesity, while at the same time, the more weight people gain, the more likely they are to need additional medications, particularly those that are obesogenic.









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