Dr. Gaby’s ‘Take’ on Hypothyroidism
In Dr. Alan R. Gaby’s milestone nutritional textbook, aptly titled Nutritional Medicine, the arguments are spelled out for diagnosing hypothyroidism when a patient has “normal” blood tests. In an eight-page chapter, Gaby raises reasonable scientific mechanisms to explain a patient’s thyroid symptoms with a normal TSH, normal T3, and normal T4 test. Gaby talks about genetic abnormalities in the two deiodinase enzymes that could potentially interfere with the body’s ability to convert T4 to the active T3 thyroid hormone. Additionally, he explains that there are two beta receptors for thyroid hormone and that these receptors can be dysfunctioning by genetic or biochemical mechanisms. Gaby cites extensive literature to support these hypotheses.









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