Preventing Bronchopulmonary Dysplasia in Preterm Infants
One hundred twelve preterm Chinese infants (mean gestational age, 29.5 weeks) were randomly assigned to receive 800 IU per day of vitamin D or no vitamin D (controls), starting within 48 hours of birth and continuing for 28 days. The incidence of bronchopulmonary dysplasia (BPD) at day 28 was 58% lower in the vitamin D group than in the control group (12.3% vs. 29.1%; p < 0.03). Compared with control, vitamin D significantly decreased serum levels of inflammatory markers (C-reactive protein, interleukin-6, and tumor necrosis factor alpha).










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