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Niacin and Cancer – How Vitamin B3 Protects and Even Helps Repair Your DNA

Niacin and Cancer – How Vitamin B3 Protects and Even Helps Repair Your DNA

by , , | Aug 1, 2022

Post Categories: Cancer Treatment and Prevention | Healthy Aging Practices | Nutrition and Lifestyle | Supplements

Although an individual’s DNA sequences cannot be changed, the expression of genes can be modified by diet, including supplementation with high-dose niacin to boost NAD levels.

Cells that have had DNA damage are frequently transformed into cancer cells due to mutation. When our tumor suppressor genes are mutated, they can no longer function, and cells can grow without regulation and become cancerous. In a healthy situation, when a cell has DNA damage, poly-ADP ribose (PAR) is added to the DNA, and the cell will stop dividing. If the DNA can be repaired, the cell may continue dividing normally. If the damage is too much, then the cell will die by apoptosis. If the DNA damage is too extreme and acute, then the cell will die by the uncontrollable and messy process of necrosis, which will then adversely affect neighboring cells, likely causing greater collateral damage to them. When the PAR polymer is formed, NAD can become depleted, and cell death occurs because cells cannot live more than a minute or two without NAD.

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Author

W. Todd Penberthy, PhD

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