Uncovering Hidden Health Issues: The Role of Food Sensitivities in Chronic Inflammation and Gut Health

Uncovering Hidden Health Issues: The Role of Food Sensitivities in Chronic Inflammation and Gut Health

by , | Aug 29, 2024

In the realm of health and wellness, we often find that one crucial factor is overlooked: the impact of food sensitivities on overall well-being. From our work at Progressive Medical Center in Dunwoody, Georgia, we’ve seen firsthand how food sensitivities, particularly those mediated by Immunoglobulin G (IgG), can significantly influence inflammation throughout the body, leading to a range of chronic health issues. Our comprehensive approach to diagnosing and addressing these sensitivities helps individuals identify the root causes of their health challenges and paves the way for more effective, personalized treatment plans.

The Role of IgG-Mediated Food Sensitivities

IgG-mediated food sensitivities are more than just a minor inconvenience; they play a substantial role in shifting cytokines, the proteins crucial for cell signaling in the immune system. Altered cytokine levels can lead to widespread inflammation, affecting various systems within the body. For instance, our studies involving patients with Irritable Bowel Syndrome (IBS) have shown that a higher number of IgG food sensitivities correlates with lower levels of IL-10 and TGF-Beta—cytokines essential for maintaining immune tolerance. When these cytokine levels are inadequate, the body’s immune response can become dysregulated, leading to chronic inflammation and a host of related health issues.

Impact on Brain Health

The implications of IgG-mediated food sensitivities extend beyond the gut. Elevated levels of Tumor Necrosis Factor-alpha (TNF-alpha), a pro-inflammatory cytokine, have been linked to behavioral issues and cognitive decline. TNF-alpha is a significant driver of inflammation, and its increased presence in the brain can contribute to conditions such as depression, anxiety, and even Alzheimer’s disease. By identifying and removing foods that trigger these inflammatory responses, we have observed notable improvements in both mental and physical health among our patients.

Gut Permeability and Chronic Conditions

One of the most critical aspects of food sensitivities is their impact on gut permeability, often referred to as “leaky gut.” When the gut lining becomes permeable, it allows larger, undigested food particles and toxins to enter the bloodstream, triggering immune responses and further inflammation. Biomarkers such as anti-lipopolysaccharide (LPS) and anti-occludin IgG and IgA antibodies are significantly associated with IgG-mediated food sensitivities. This correlation highlights the importance of gut-based permeability in the development of chronic conditions, including autoimmune diseases and compromised immune function.

Why Testing is Essential

Before starting any dietary or nutritional regimen, it’s crucial to understand the underlying sensitivities and imbalances in the gut. Without this knowledge, attempts to improve health through diet may be misguided, leading to continued inflammation and chronic health issues. At Progressive Medical Center, we offer comprehensive allergy screening, food sensitivity testing, and gut microbiome analysis as part of our holistic approach to health. These tests provide invaluable insights that allow us to create personalized treatment plans tailored to each individual’s unique needs.

The Cart Before the Horse

Food sensitivities may be the hidden culprits behind many chronic health issues. By addressing these sensitivities through targeted testing and personalized dietary interventions, individuals can take a significant step toward reducing inflammation, improving gut health, and enhancing overall well-being. At Progressive Medical Center, we are at the forefront of this integrative approach, dedicated to helping our patients uncover and address the root causes of their health challenges.

For more information on the importance of allergy testing, watch our video here: Dr. Gez Agoli explains the importance of allergy testing.

Visit our clinic page to order your analysis: Progressive Medical Center – Allergy and Sensitivity Test.

Authors

  • Cheryl Burdette, ND

    Dr. Burdette is Director of Education at Progressive Medical Center, one of the largest integrative clinics in the Southeast. She is the co-founder of Precision Point Diagnostics, a laboratory that focuses on gut based health and wellness. There she designs clinical profiles and trains clinicians on their utilization. She has a rich history in the integrative medicine laboratory space. She designed and teaches the clinical curriculum for Origins Incubator, a practice management group, that has helped to launch many successful practitioners. She is the Educational Director and on the board of advisors for Xymogen, a physician line pharmaceutical. She is on the board of advisors for TheraDura Diagnostik, a German based lab company. She serves on IRB boards, is involved in study design and translational research, and has lectured extensively worldwide. She directs an accredited Naturopathic residency at Progressive. Her passion is teaching about the practice of Integrative and Naturopathic Medicine, to increase awareness of evidenced-based natural therapies, to both rule in and rule out tools that are effective in patient care.

    View all posts
  • Gez Agolli, DrPH PhD MBBS

    Dr Gez Agolli is the Co-founder of Progressive Medical Centers in Atlanta (the largest integrative clinic in the SE for over 25 years treating over 45,000 patients) & co-founder of Precision Point Diagnostics (High complexity CLIA-certified lab). Dr. Agolli is passionate about integrative medicine and believes we live in an exciting time in medical history. Why? Medical science is finally recognizing that “Chronic” disease is not inherited but mostly due to a multitude of issues such as immune deficiency, toxic exposure, inflammation, hormonal imbalance, nutritional deficiency, stress, and gut dysbiosis "Leaky Gut". "ROOT Cause Medicine" Therefore, Dr Agolli has devoted his professional career to developing integrative clinics & training over 200 practitioners to think outside the box to practice functional/integrative medicine. He truly embraces this philosophy personally and professionally. Dr Agolli has hosted over 500 radio shows and podcasts (Rethink Myhealth) discussing current medical topics that educate and inform the general public on cutting-edge, evidence-based medical treatments and therapies. He currently mentors and coaches 15 practitioners (MDs, NPs, NDs, RDs, DCs) and a staff of over 75.

    View all posts

Already Subscribed?

Search

Formatting updates are ongoing for older articles.

Author

Featured Articles

Where are your Clinical Trials?

It has proven to be difficult, if not impossible, to proceed to full-scale randomized controlled trials (RCTs) for most of the natural methods that cannot be patented or otherwise monopolized. 

A Renewed Focus on Self-Help for Healing

As the producer of The Moss Report, the year leading up to the Covid-19 pandemic was filled with anticipation and excitement. We had invested years of hard work and significant resources into two major projects: our feature film, Immunotherapy: The Battle Within, and...

Issue Archives

Event Calendar

  • 2026 Association of Natural Health Conference

    Douglasville Conference Center Douglasville, GA, United States

    "From Practitioner to Leader: Clinical Excellence, Business Mastery & Sustainable Practice" Discover how clinical excellence, business mastery, and sustainable systems can help practitioners grow into confident leaders and build practices designed for long-term impact. Why Attend? Three days of learning, connection, and growth designed for every stage of your practice journey. Learn from Leading Voices Gain insights from top experts in natural health, holistic wellness, and functional medicine. Hands-On Learning Participate in in-depth workshops, real-world case studies, and interactive sessions you can apply immediately. Meaningful Networking Connect with like-minded professionals, students, and exhibitors who share your passion for natural health. Practical Tools & Approaches Explore new strategies and tools to elevate both your practice and your own health journey. Who Should Attend? This conference is built for a wide community of natural health professionals, educators, and advocates - wherever you are in your journey. Licensed & Clinical Practitioners Doctors, chiropractors, acupuncturists, naturopaths, and functional or integrative medicine practitioners looking to sharpen clinical skills and grow into stronger practice leaders. Allied Health Professionals Bio-feedback technicians and other allied practitioners seeking hands-on training and the latest tools in natural and holistic care. Educators & Students Natural health educators and students entering the […]

  • Food as Medicine Global 2026

    Virtual Event

    Join health professionals, farmers, food producers, researchers, educators, nonprofit leaders, chefs, policymakers, community organizers, food advocates, public health practitioners, nutritionists, and other changemakers as we convene to share knowledge, build partnerships, and explore new possibilities for improving health, strengthening communities, and creating more equitable and sustainable food systems. This year’s program features inspiring speakers and practical examples of collaboration at the intersection of food, health, social justice, and planetary well-being. Together, we’ll explore innovative approaches to Food as Medicine, community-led initiatives, nutrition, public health, regenerative agriculture, and equitable access to healthy food. Whether you work in health care, agriculture, food production, education, research, policy, or community development, you will discover new ideas, meaningful connections, and practical strategies to advance healthier, more resilient communities. Virtual  |  Join from anywhere in the world Check out the Program: https://tinyurl.com/Food-as-Medicine-for-All

  • The Midlife Women’s Health Summit: Evidence-Based Menopause Care in the Era of Longevity Medicine

    The Ritz-Carlton, Pentagon City 1250 S Hayes St, Arlington, VA, United States
    Hybrid Event

    Menopause Care in the Longevity Era Longevity medicine is everywhere right now. Supplements, protocols, influencer clinics, patients walking in with questions about interventions their doctors have never heard of. What's missing from most of it is the evidence. The Midlife Women's Health Summit is three days on what the research actually says about menopause care when you add a longevity lens. What works, what doesn't, what's being oversold, and what to tell the patient sitting in front of you. Co-chaired by Lisa Larkin, MD, FACP, MSCP, IF, Jen Gunter, MD, FRCS(C), FACOG, DABPM, ABPMR, and Lauren Streicher, MD, FACOG, MSCP; three of the clearest voices in women's health on separating data from marketing.

    $995 – $1299

Related Posts

Medicine, The Microbiome, and Homeopathy

By Ronald Whitmont, MD – Just as we have reached a watershed moment and a “tipping point” in our understanding of global ecology and climate change, we have reached a similar critical event horizon with respect to dysfunctional medical practices; and it is time to take evasive action.

Read More

Restore the Gut – A Bio-Electric Chemistry Explanation to Identify the Cause of Everyday Chronic GI Complaints

By Darrell SCS Misak, ND, RPh – Naturopathic medicine has always been right: restore the gut first and you will potentially interrupt the entire cascade before it has the chance to write itself into a patient’s biochemistry or gene expression, and as Dr. Carey Reams himself maintained, into the very deficiencies that underlie all diseases.

Read More

Hawthorn (Crataegus oxyacantha and other species)

By Donnie Yance – Hawthorn has been used for centuries as a cardiovascular medicine, and modern research is revealing just how broad its effects may be. From heart failure and hypertension to metabolic health, inflammation, and healthy aging, this traditional botanical has an impressive and growing evidence base.

Read More

My Keto Journey: Two Weeks In

By Ben Moss – I’ve recommitted myself to a low-carbohydrate lifestyle and it’s not easy! I’m paying close attention to what happens as my body transitions into nutritional ketosis. Two weeks in, I can feel the difference.

Read More

0 Comments

Submit a Comment