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Russell Jaffe, MD, PhD, received his AB, MD (with senior thesis honors), and PhD (In biochemistry and physiology) from Boston University. Dr. Jaffe served his medical internship at University Hospital and was awarded the US Public Health Service Officer Commission, assigned to the Clinical Center of the National Institutes of Health in June 1973. While at the Clinical Center, Dr. Jaffe served his residency in clinical pathology. He is board certified in clinical and subspecialty certified in chemical pathology. Dr. Jaffe remained on the permanent senior staff of the NIH Clinical Pathology Department, where he continued method innovation and was active in collaborative research with the Laboratory of Experimental Atherosclerosis (of the Heart, Lung, and Blood Institute). Concurrently, Dr. Jaffe’s interests in the mechanisms of health and the evoking of human healing responses led him to apprentice in such healing arts as acupuncture; mindfulness; massage; music, art, and color therapy; and a variety of eclectic therapeutic approaches. In addition, Dr. Jaffe performed innovative studies of platelet function and blood clotting in relation to the origins of coronary artery and cardiovascular diseases. Among the tests that he developed are the early colon cancer-screening test using occult blood detection not interfered with by vitamin C consumption, as well as a variety of tests related to the blood clotting and immune defense and repair systems. Dr. Jaffe developed the first method of measuring cell-mediated immunity using a modified ELISA system in a lymphocyte mitogenesis/blastogenesis brief cell culture known as lymphocyte response assays (LRA). This LRA by ELISA/ACT provides an “immunologic fingerprint” of items to which the body is reactive or tolerant. Dr. Jaffe has contributed over 100 symposium-invited talks, scientific articles, or book chapters. He received the J. D. Lane award for original research from the USPHS, the Merck Sharp and Dohme Excellence in Research Award, and in 2002 the International Research Scientist of the Year, among other recognitions for his investigations. Dr. Jaffe is a fellow of the Health Studies Collegium and director of ELISA/ACT Biotechnologies LLC and PERQUE LLC in Ashburn, Virginia. He may be reached at 800-525- 7372 ext. 5101, and rjaffe@ELISAACT.com  or rjaffe@PERQUE.com.

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Featured Articles

Where are your Clinical Trials?

It has proven to be difficult, if not impossible, to proceed to full-scale randomized controlled trials (RCTs) for most of the natural methods that cannot be patented or otherwise monopolized. 

A Renewed Focus on Self-Help for Healing

As the producer of The Moss Report, the year leading up to the Covid-19 pandemic was filled with anticipation and excitement. We had invested years of hard work and significant resources into two major projects: our feature film, Immunotherapy: The Battle Within, and...

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  • Practical Clinical Skills in Neurotransmitter Optimization: Clinical Herbalism for Mood, Cognition & Aging

    Virtual Event

    Don't miss this two-part virtual symposium, being held Sept. 26 & Oct. 17, 2026! Mental health and neurocognitive disorders remain among the most prevalent and inadequately addressed challenges in modern clinical practice.  This intensive, expert-led symposium provides a comprehensive, clinically grounded framework for integrating herbal and nutraceutical strategies into mental health care. Attendees gain a working understanding of how targeted herbal interventions modulate key neurotransmitter systems, including serotonin, dopamine, GABA, and cortisol, and how to apply these therapies strategically, whether as adjuncts to pharmaceuticals or as standalone options. Clinical applications span a wide spectrum, from anxiety and depression to Parkinson’s-related motor symptoms and age-associated cognitive decline, with a strong emphasis on practical implementation and patient-specific protocol design.

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