SubscribeorLogin

Testosterone Notes

by , , , , , | Jan 1, 2011

Post Categories: Aging and Longevity | Bioidentical Hormones

Notes

  1. Carnahan RM, Perry PJ. Depression in aging men: the role of testosterone. Drugs Aging. 2004;21(6):361–376.

  2. Orengo CA, Fullerton G, et al. Male depression: a review of gender concerns and testosterone therapy. Geriatrics. 2004;59(10):24–30.

  3. Zarrouf FA, Artz S, et al. Testosterone and depression: systematic review and meta-analysis. J Psychiatr Pract. 2009;15(4):289–305.

  4. Cherrier MM, Asthana S, et al. Testosterone supplementation improves spatial and verbal memory in healthy older men. Neurology. 2001;57(1):80–88.

  5. Cherrier MM, Matsumoto AM, et al. Testosterone improves spatial memory in men with Alzheimer disease and mild cognitive impairment. Neurology. 2005;64(12):2063–2068.

  6. Beer TM, Bland LB, et al. Testosterone loss and estradiol administration modify memory in men. J Urol. 2006;175(1):130–135.

    Advertisement

  7. Lim D, Flicker L, et al. Can testosterone replacement decrease the memory problem of old age? Med Hypotheses. 2003;60(6):893–896.

  8. Thompson IM, Goodman PJ, Tangen CM, et al. The influence of finasteride on the development of prostate cancer. N Engl J Med. 2003;349(3):215–224.

  9. Wilt TJ et al. Five-alpha-reductase inhibitors for prostate cancer prevention. Cochrane Database Syst Rev. 2008 Apr 16;(2):CD007091.

  10. Weihua Z, Lathe R, Warner  M, Gustafsson JA. An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth. Proc Natl Acad Sci USA. 2002;99:13589–13594.

  11. Zhu X, Leav I, Leung YK, et al. Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis. Am J Pathol. 2004;164:2003–2012.

  12. Imamov O, Morani A, Shim GJ, et al. Estrogen receptor beta regulates epithelial cellular differentiation in the mouse ventral prostate. Proc Natl Acad Sci U S. 2004;101:9375–9380.

  13. Imamov O, Lopatkin N, Gustafsson JA. Estrogen receptor β in prostate cancer. N Engl J Med. 2004; 351:2773–2774.

  14. Imamov O, Shim G-J, Warner M, Gustafsson JA. Estrogen receptor beta in health and disease. Biol Reprod. November 1, 2005;73(5):866–871.

  15. Armamento-Villareal RC, Napoli N, et al. The oxidative metabolism of estrogen modulates response to ERT/HRT in postmenopausal women. Bone. 2004;35(3):682–688.

  16. Castagnetta LA,  Granata OM, et al. Tissue content of hydroxyestrogens in relation to survival of breast cancer patients. Clin Cancer Res. 2002;8(10):3146–3155.

  17. Wellejus A, Olsen A, et al. Urinary hydroxyestrogens and breast cancer risk among postmenopausal women: a prospective study. Cancer Epidemiol Biomarkers Prev. 2005;14(9):2137–2142.

Authors

  • View all posts
  • View all posts
  • View all posts

  • Jill C. Carnahan, MD, ABIHM, IFMCP, was dually board certified in Family Medicine in 2006-2016 and in Integrative Holistic Medicine since 2005. She founded the Methodist Center for Integrative Medicine in Peoria, Illinois in 2009 and worked there as medical director. Then in 2010, she moved to Boulder, Colorado and opened Flatiron Functional Medicine where she has a widely sought-after medical practice with a broad range of clinical service including nutritional consultations, chiropractic therapy, naturopathic medicine, acupuncture, and massage therapy.

    Dr. Jill is survivor of both breast cancer and Crohn’s disease and passionate about teaching patients how to live well and thrive in the midst of complex and chronic illness. She is also a widely sought-after inspirational speaker and travels around the world to teach physicians the principles of personalized and functional medicine. She has been featured in Shape Magazine, Parade, Forbes, MindBodyGreen, First for Women, Townsend Letter, and the Huffington Post as well as seen on NBC News and Health segments with Joan Lunden. She recently published her prescriptive memoir, Unexpected: Finding Resilience Through Functional Medicine, Science, and Faith, was published in 2023.

    For more articles and information by Dr. Jill Carnahan - visit https://www.jillcarnahan.com and Subscribe to Dr. Jill LIVE on Dr. Jill Carnahan’s YouTube Channel

    View all posts
  • View all posts
  • View all posts

Already Subscribed?

Log In

Search

Formatting updates are ongoing for older articles.

Author

Brenda Leung, ND

Featured Articles

Where are your Clinical Trials?

It has proven to be difficult, if not impossible, to proceed to full-scale randomized controlled trials (RCTs) for most of the natural methods that cannot be patented or otherwise monopolized. 

A Renewed Focus on Self-Help for Healing

As the producer of The Moss Report, the year leading up to the Covid-19 pandemic was filled with anticipation and excitement. We had invested years of hard work and significant resources into two major projects: our feature film, Immunotherapy: The Battle Within, and...

Issue Archives

Event Calendar

Events

Today

  • Integrative Cancer Symposium 2026 – Believe BIG

    Sheraton, Towson MD Towson, MD, United States

    Optimize Your Health. Transform Your Future. Join us for this dynamic one-day experience designed for anyone seeking to take a proactive, whole-body approach to health. Integrative oncology is a dynamic and rapidly evolving field, unveiling groundbreaking discoveries and new possibilities every day. This year’s one-day conference will take place at the Sheraton in Towson, Maryland from 9am – 5pm and offers both in-person and virtual attendance options. This event brings together leading experts in integrative oncology, functional medicine, and wellness. Discover cutting-edge approaches to prevention, treatment, recovery, and whole-person wellness at the Integrative Cancer Symposium Believe Big 2026. Learn from leading clinicians, researchers, and innovators in integrative oncology as they explore emerging therapies, metabolic and lifestyle approaches, mistletoe therapy, nutrition, environmental health, mindset, and more. Whether you are navigating cancer personally, supporting a loved one, or simply looking to optimize your health and reduce future risk, this powerful one-day experience offers practical tools, fresh insights, and meaningful connection.

  • PLMI 14th Annual Thought Leaders Consortium

    Loews Coronado Bay Resort 4000 Coronado Bay Rd, Coronado, CA, United States

    The 14th Annual Thought Leaders Consortium marks the culminating chapter of PLMI’s three-year exploration into the biology of immuno-metabolism, epigenetic regulation, and human longevity. Building on the 2024 and 2025 Consortia—which reframed chronic disease through immune-metabolic dysfunction and diet- and environment-driven epigenetic remodeling—this year’s gathering places mitochondria at the center of health, disease, and aging. Once viewed simply as the cell’s energy producers, mitochondria are now recognized as dynamic, epigenetically responsive organelles that integrate nutrition, environmental exposures, immune activation, stress signaling, physical activity, and circadian inputs into a unified metabolic-immune system. Disruption of mitochondrial function is increasingly implicated in fatigue syndromes, chronic pain, immune dysregulation, neurodegeneration, infertility, metabolic disease, accelerated aging, and diminished stress resilience. This advanced, science-driven Consortium convenes world-leading experts to explore mitochondrial biology as the cornerstone of immuno-metabolic resilience. Attendees will gain cutting-edge insights into mitochondrial signaling, mito-nuclear communication, and metabolic flexibility—alongside clinically actionable frameworks for restoring cellular vitality, reversing biological aging trajectories, and extending healthspan. Through deep scientific exploration and translational clinical strategy, the 2026 Thought Leaders Consortium will equip practitioners and researchers with the knowledge needed to redefine assessment, intervention, and long-term outcomes in personalized and lifestyle medicine.

    $650

  • Practical Clinical Skills in Neurotransmitter Optimization: Clinical Herbalism for Mood, Cognition & Aging

    Virtual Event

    Join us for the second part of this two-part virtual symposium! Mental health and neurocognitive disorders remain among the most prevalent and inadequately addressed challenges in modern clinical practice.  This intensive, expert-led symposium provides a comprehensive, clinically grounded framework for integrating herbal and nutraceutical strategies into mental health care. Attendees gain a working understanding of how targeted herbal interventions modulate key neurotransmitter systems, including serotonin, dopamine, GABA, and cortisol, and how to apply these therapies strategically, whether as adjuncts to pharmaceuticals or as standalone options. Clinical applications span a wide spectrum, from anxiety and depression to Parkinson’s-related motor symptoms and age-associated cognitive decline, with a strong emphasis on practical implementation and patient-specific protocol design.

Full Event Calendar

Submit Your Event

Related Posts

Literature Review and Commentary

By Alan R. Gaby, MD – From eggs and Alzheimer’s risk to iodine during pregnancy, bromelain after dental surgery, and tomatoes for fatty liver, this collection explores intriguing connections between nutrition and health. We also examine questions surrounding CoQ10 for depression, sex-specific responses to iron therapy, goat milk formula and eczema, and celiac disease in unexplained cirrhosis.

Read More

Aug 31, 2026

You Deserve a Beautiful Life

by Gary Null, PhD – How many times have we gone against the current of our own being? You know you should do A, but you are conditioned to do B.

You are fighting it because the conditioned self is conditioned from a place of fear. And fear will always win if we give in to it.

Read More

Aug 31, 2026

Beyond the Plastic: Test, Mitigate, Restore, Measure

By Chris D. Meletis, ND – Recent investigations have identified microplastic particles in human blood, placental tissue, lung tissue, brain, liver, kidney, breast milk, and atherosclerotic plaque. While these findings confirm that human exposure occurs and that at least some particles can enter biological systems, the clinical implications remain an active area of investigation.

Read More

Aug 14, 2026

0 Comments

Submit a Comment

Pin It on Pinterest

Share This