I was pleased to read Jacob Schor acknowledge that there are benefits of antioxidants (August 26, 2023). I was disappointed that he did not elaborate on those benefits and disappointed by the incomplete and, at points, misleading arguments presented. Readers may be interested to know that Dr. Harman and his wife, coincidentally, both led productive lives into their 90s (Denham passed at the age of 98 after a short illness). Many antioxidant supplement enthusiasts in the tradition of Dr. Pauling and Dr. Harman coincidentally led productive lives past the age of 80. The difference between increasing the wellness span within one’s lifespan vs. simply increasing one’s lifespan is also not mentioned. Arguably, increasing one’s wellness span is where wisely chosen supplemental antioxidants have the biggest benefit. Of course, assaults, motor vehicle accidents, and a multitude of other threats to human survival are not impacted by the victim’s antioxidant status, fruit and vegetable intake, or gut microbiome.
Where are your Clinical Trials?
It has proven to be difficult, if not impossible, to proceed to full-scale randomized controlled trials (RCTs) for most of the natural methods that cannot be patented or otherwise monopolized.










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