Post Categories: Herbal Medicine

1. Loch E, Selle H, Boblitz N. Treatment of premenstrual syndrome with a phytopharmaceutical formulation containing Vitex agnus castus. J Womens Health Gend Based Med . 2000;9:315–320.

2. Berger D, Schaffner W, Schrader E, Meier B, Brattstrom A. Efficacy of Vitex agnus castus L. extract Ze 440 in patients with pre-menstrual syndrome. Arch Gynecol Obstet . 2000;264:150–153.

3. Halaska M, Beles P, Gorkow C, Sieder C. Treatment of cyclical mastalgia with a solution containing a Vitex agnus castus extract: results of a placebo-controlled double-blind study. Breast . 2000 ;8:175–181.

4. Atmaca M, Kumru S, Tezcan E. Fluoxetine versus Vitex agnus castus extract in the treatment of premenstrual dysphoric disorder. Hum Psychopharmacol . 2003;18:191–195.)

5. Schellenberg R. Treatment for the premenstrual syndrome with agnus castus fruit extract: prospective, randomised, placebo controlled study. Br Med J . 2001;322:134–137.

6. He Z, Chen R, Zhou Y, et al. Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China. Maturitas . 2009 ;63:99–103 .

7. Van Die, M, Bone K, Burger H, et al. Effects of a combination of Hypericum perforatum and vitex agnus-castus on PMS-like symptoms in late-perimenopausal women: Findings from a subpopulation analysis. J Altern Comp Med . 2009;15(9):1045–1048.

8. Probst V Roth O. On a plant extract with hormonelike effect. Dtsch Med Wschr. 1954 ;79(35):1271–1274.

9. Borrelli F, Ernst E. Cimicifuga racemosa: a systematic review of its clinical efficacy. Eur J Clin Pharmacol . 2002;58:235–241.

10. Huntley A, Ernst E. A systematic review of herbal medicinal products for the treatment of menopausal symptoms. Menopause . 2003;10:465–476.

11. Liske E, Hanggi W, Henneicke-von Zepelin H, et al. Physiological investigation of a unique extract of black cohosh: a 6 month clinical study demonstrates no systemic estrogenic effect. J Womens Health Gend Based Med . 2002;11:163–174.

12. Osmers R, Friede M, Liske E, Schnitker J, et al. Efficacy and safety of isopropanolic black cohosh extract for climacteric symptoms. Obstet Gynecol . 2005;105:1074–1083.

13. Frei-Kleiner S, Schaffner W, Rahlfs V, et al. Cimicifuga racemosa dried ethanolic extract in menopausal disorders: a double-blind placebo-controlled clinical trial. Maturitas . 2005;16;51(4):397–404.

14. Wuttke W, Seidlova-Wuttke D, Gorkow C. The Cimicifuga preparation BNO 1055 vs. conjugated estrogens in a double-blind placebo-controlled study: effects on menopause symptoms and bone markers. Maturitas . 2003;44:S67–77.

15. Jacobson J, Troxel A, et al. Randomized trial of black cohosh for the treatment of hot flushes among women with a history of breast cancer. J Clin Oncol . 2001;19:2739–2745.

16. Stolze H. An alternative to treat menopausal symptoms with a phytotherapeutic agent. Med Welt. 1985;36:871–874.

17. Wuttke W, Gorkow C, Seidlova-Wuttke D. Effects of black cohosh on bone turnover, vaginal mucosa, and various blood parameters in postmenopausal women: a double-blind, placebo-controlled, and conjugated estrogens-controlled study. Menopause. 2006;13(2):185–196.

18. Pockaj B et al. Phase III double-blind, randomized, placebo-controlled crossover trial of black cohosh in the management of hot flashes: NCCTG Trial NO1CC1. J Clin Oncol . 2006;24:2836–2841.

19. Newton K, Reed S, LaCroix A, Grothaus L, Ehrlich K, Guiltinan J. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med. 2006;145(12) :869–879.

20. Uebelhack R, Jens-Uwe Blohmer, et al. Black cohosh and St. john’s wort for climacteric complaints. Obstet Gynecol . 2006;107:247–255.

21. Chung D, Kim H, Park K, et al. Black cohosh and St. John’s wort (GYNO-Plus) for climacteric symptoms. Yonsei Med J . 2007;48(2):289–294.

22. Bai W, Henneicke-von Zepelin H, Wang S, et al. Efficacy and tolerability of a medicinal product containing an isopropanolic black cohosh extract in Chinese women with menopausal symptoms: A randomized, double blind, parallel-controlled study versus tibolone. Maturitas . 2007 ;58:31–41.

23. Cancellieri F,De Leo V, Genazzani A, et al. Efficacy on menopausal neurovegetative symptoms and some plasma lipids blood levels of an herbal product containing isoflavones and other plant extracts. Maturitas . 2007 ;56:249–256

24. Reed S, Newton K, LaCroix A, et al. Vaginal, endometrial, and reproductive hormone findings: randomized, placebo-controlled trial of black cohosh, multibotanical herbs, and dietary soy for vasomotor symptoms: the Herbal Alternatives for Menopause (HALT) Study. Menopause . 2008;15(1):51–58.

25. Rostock M, Fischer J, Mumm A, et al. Black cohosh (Cimicifuga racemosa) in tamoxifen-treated breast cancer patients with climacteric complaints – a prospective observational study. Gynecol Endocrinol. 2011 Jan 13;

26. Rebbeck T, Troxel A, Norman S, et al. A retrospective case-control study of the use of hormone-related supplements and association with breast cancer. Int. J. Cancer . 2007 ;120:1523–1528.

27. Mahady G, Low Dog T, Barrett M, et al. United States Pharmacopeia review of the black cohosh case reports of hepatotoxicity. Menopause . 2008;15(4):628–638.

28. Black cohosh. In: Blumenthal M, ed. The ABC Clinical Guide to Herbs. Austin, TX: American Botanical Council; 2003:15–22.

29. Rockwell S, Liu Y, Higgins S. Alteration of the effects of cancer therapy agents on breast cancer cells by the herbal medicine black cohosh. Breast Cancer Res Treat . 2005;90(3) :233–239.

30. Abdali K, Khajehei M, Tabatabaee R. Effect of St. John’s wort on severity, frequency, and duration of hot flashes in premenopausal, perimenopausal and postmenopausal women: a randomized, double-blind, placebo-controlled study. Menopause . 2010;17(2) :326–331.

31. Al-Akoum M, Maunsell E, Verreault R, Provencher L, Otis H, Dodin S. Effects of Hypericum perforatum (St. John’s wort) on hot flashes and quality of life in perimenopausal women: a randomized pilot trial

.

Menopause. 2009 Mar–Apr;16(2):307–314.

32. Grube B, Walper A, Whatley D. St. John’s wort extract: Efficacy for menopausal symptoms of psychological origin. Adv Ther. 1999;16:177.

33. Boblitz N, Schrader E, Henneicke-Von Zepelin H, et al. Benefit of a fixed drug combination containing St. John’s wort and black cohosh for climacteric patients-results of a randomised clinical trial . Poster presentation from 6th Annual Symposium on Complementary Health Care, Exeter, England, December 2–4 1999. Focus Alt Comp Ther . 2000;5(1):85–86.

34. Uebelhack R, Jens-Uwe Blohmer, et al. Black cohosh and St. John’s wort for climacteric complaints. Obstet Gynecol . 2006;107:247–255.

35. Chung D, Kim H, Park K, et al. Black cohosh and St. John’s wort (GYNO-Plus) for climacteric symptoms. Yonsei Med J . 2007;48(2):289–294.

36. Briese V, Stammwitz U, Friede M, et al. Black cohosh with or without St. John’s wort for symptom-specific climacteric treatment. Results of a large-scale, controlled, observational study. Maturitas . 2007;57:405–414.

37. Canning S, Waterman M, Orsi N, et al. The efficacy of Hypericum perforatum (St John’s Wort) for the treatment of premenstrual syndrome. CNS Drugs . 2010 ;24(3):207–225.

38 . Stevinson C, Ernst E. A pilot study of Hypericum perforatum for the treatment of premenstrual syndrome. BJOG . 2000;107:870–876.

39 . Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Alternative and Complementary Med . 2009 ;15(2):129–132.

40 . Rahnama P, Montazeri A, Fallah Huseini H, Kianbakht S, Naseri M. Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complement Altern Med. July 10, 2012;12(1):92

41 . Ozgoli G, Goli M, Simbar M. Effects of ginger capsules on pregnancy, nausea and vomiting. J Altern Comp Med. 2009;15(3):243–246

42 . Kuriyama S, Shimazu T, Ohmori K, et al. Green tea consumption, and mortality due to cardiovascular disease, cancer, and all mortality causes in Japan: the Ohsaki study. JAMA . 2006 . Sept 13 ;296 (10) :1255–1265.

43. Paschka A et al. Induction of apoptosis in prostate cancer cell lines by the green tea components, epigallocatechine-3-gallate. Cancer Lett. 1998;130(1–2):1–7

44 . Hibasami H et al. Induction of apoptosis in human stomach cancer cells by green tea catechins. Oncol Rep. 1998;5:527–529.

45 . Ahmad N et al. Green tea constituent epigallocatechin-3-gallate and induction of apoptosis and cell cycle arrest in human carcinoma cells. J Natl Cancer Inst. 1997;89:1881–1886.

46 . Yang G et al. Inhibition of growth and induction of apoptosis in human cancer cell lines by tea polyphenols. Carcinogenesis. 1998;19:611–616.

47 . Chen Z et al. Green tea epigallocatechin gallate shows a pronounced growth inhibitory effect on cancerous cells but not on their normal counterparts. Cancer Lett. 1998;129:173–179.

48 . Liao S, Umekita Y, Guo J, et al. A growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate. Cancer Lett. 1995 ;96:297–301.

49 . Kavanagh, K, Hafer L, Kim D, et al. Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. J Cell Biochem . 2001 ;82 :387–398.

5 0. Hirose M, Hoshiya T, Akegi K, et al. Inhibition of mammary gland carcinogenesis by green tea catechins and other naturally occurring antioxidants in female Sprague-Dawley rats pretreated with 7,12-dimethylbenz(a)anthraacene. Cancer Lett. 1994;83:149–156.

51 . Kavanagh, K, Hafer L, Kim D, et al. Green tea extracts decrease carcinogen-induced mammary tumor burden in rats and rate of breast cancer cell proliferation in culture. J Cell Biochem. 2001 ;82:387–398.

52 . Araki R, Inoue S, Osborne M, Telang, N. Chemoprevention of mammary preneoplasia. In vitro effects of a green tea polyphenol. Ann NY Acad Sci. 1995;768;215–222.

53 . Sartippour M, Zhi-Ming S, Heber D, et al. Green tea inhibits vascular endothelial growth factor induction inhuman breast cancer cells. N Nutr . 2002;132:2307–2311.

54 . Pianetti S, Guo S, Kavanagh K, Sonenshein G. Green tea polyphenol epigallocatechin-3 gallate inhibits Her-2/Neu signaling, proliferation, and transformed phenotype of breast cancer cells. Cancer Res . 2002;62:652–655

55 . Nakachi K, Suemasu K, Suga K, et al. Influence of drinking green tea on breast cancer malignancy among Japanese patients. Japan J Cancer Res. 1998;89:254–261

56 . Sun C, Yuan J, Koh W, Yu M. Green tea, black tea and breast cancer risk: a meta-analysis of epidemiological studies. Carcinogenesis . 2006;27(7) :1310–1215.

57 . Larsson S, Wolk A. Tea consumption and ovarian cancer risk in a population-based cohort. Arch Intern Med . 2005;165(22) :2683–2686

58 . Zhang M, Lee A, Binns C, Xie X. Green tea consumption enhances survival of epithelial ovarian cancer. Int J Cancer . 2004;112(3) :465–469.

59 . Sah J, Balasubramanian S, Eckert R, Rorke E. Epigallocatechin-3-gallate inhibits epidermal growth factor receptor signaling pathway. Evidence for direct inhibit of ERK ½ and AKT kinases. J Biol Chem . 2004;79(13) :12755–12762.

60 . Ahn W, Huh S, Bae S, et al. A major constituent of green tea, EGCG, inhibits the growth of a human cervical cancer cell line, CaSki cells, through apoptosis G(1) arrest, and regulation of gene expression. DNA Cell Biol . 2003;22(3) :217–224.

61. Yokoyama M, Noguchi M, Nakao Y, et al. The tea polyphenol, (-) – epigallocatechin gallate effects on growth, apoptosis, and telomerase activity in cervical cell lines. Gynecol Oncol . 2004;92(1) :197–204.

62. Ahn W, Yoo J, Huh S, et al. Protective effects of green tea extracts (polyphenon E and EGCG) on human cervical lesions. Eur J Cancer Prev. 2003;12(5) :383–390.

63 . Dulloo A et al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-hour energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1990;70:1040–1045

64 . Nigata C, Kabuto M, Shimizu H. Association of coffee, green tea, and caffeine intakes with serum concentrations of estradiol and sex hormone-binding globulin in premenstrual Japanese women. Nutr Cancer. 1998;30(1) :21–24.

Dr. Tori Hudson graduated from the National College of Naturopathic Medicine (NCNM) in 1984 and has served the college in many capacities over the last 28 years. She is currently a clinical professor at NCNM and Bastyr University; has been in practice for over 28 years; and is the medical director of the clinic A Woman’s Time in Portland, OR, and director of research and development for Vitanica, a supplement company for women. She is also a nationally recognized author, speaker, educator, researcher, and clinician.

Authors

  • Blanche Grube, DDS, PhD

    Dr. Blanche has been trained by and worked with Dr. Hal Huggins (Author of It’s All in Your Head) for decades, and together they developed the Huggins-Grube Protocol, which includes doing a “Full Dental Revision.”

    Dr. Blanche D. Grube is the past president of the International Academy of Biological Dentistry and Medicine. She has published scientific papers, including presenting research at the prestigious International Conference on Mercury as a Global Pollutant. She continues to lecture worldwide, training dentists on the Huggins-Grube Protocol and “Full Dental Revisions.”

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  • Christine Schaffner, ND

    Dr. Christine Schaffner is a board-certified naturopathic doctor who has helped thousands of people recover from chronic or complex illnesses. Through online summits, her Spectrum of Health podcast, network of Immanence Health clinics, and renowned online programs, Dr. Schaffner goes beyond biological medicine, pulling from all systems of medicine and healing modalities–helping patients reclaim their wellness and reveal their brightest light.

    Dr. Schaffner completed her undergraduate studies in pre-medicine and psychology at the University of Virginia in Charlottesville and her Doctor of Naturopathic Medicine at Bastyr University in Seattle, Washington.

    With her diverse skill set, Dr. Schaffner seeks to improve access, outcomes, and speed of recovery for patients struggling with chronic, complex, and mystery illnesses. Patients travel from all around the world to reclaim their wellness using her Ecosystem & Terrain, Energy Analysis, Clear Blocks, Optimize Flow (EECO) methodology.

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  • Frank Shallenberger, MD, HMD

    Frank Shallenberger, MD, HMD, graduated from the University of Maryland School of Medicine in 1973. He is the president of the American Academy of Ozonotherapy and served as a charter member of the International Scientific Committee on Ozone Therapy. Dr. Shallenberger developed Prolozone®, an injection technique that has been shown to alleviate pain and regenerate degenerated joints, spines, tendons, and soft tissues. He has been teaching annual training seminars in ozone therapy to practitioners from all over the world for 23 years.

    Dr. Shallenberger has authored several indexed papers on ozone therapy and has also written Principles and Application of Ozone Therapy – A Practical Guideline For Physicians and The Ozone Miracle. He is the editor of Second Opinion medical newsletter, and author of The Type 2 Diabetes Breakthrough and Bursting With Energy, both of which are in their fourth printing.

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  • Gottfried H. Kellerman, PhD
  • J.E. Block, MD
  • Jenna C Henderson, ND

    Dr. Jenna Henderson’s practice, Holistic Kidney, is dedicated to the unique needs of renal patients. A kidney patient herself since 1993, she has experienced all stages of kidney disease firsthand, including 20+ years on dialysis. She is a graduate of the University of Bridgeport, and holds a CT state license.
    Dr. Henderson seeks to bridge the gap between mainstream nephrology and natural medicine. Dr. Henderson has lectured extensively across the U.S. to doctors, kidney patients, and kidney professionals. Her articles have been published in Townsend Letter, Natural Medicine Journal and Naturopathic Doctors New & Reviews.
    Holistic Kidney does telemedicine, with patients on six continents. She works with all stages including chronic kidney disease patients, patients on dialysis and those with a transplanted kidney. In her practice she helps patients sort through often conflicting information to understand what is appropriate for their individual needs and stage of kidney function.

    View all posts
  • Virginia Osborne, ND
  • W. A. Shrader, MD

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