1. Introduction
The pomegranate (Punica granatum L.) stands as one of humanity’s oldest cultivated fruits, with archaeological evidence of its consumption dating back over 5,000 years. Throughout recorded history, pomegranate has occupied a unique position in traditional medicine systems across diverse cultures, from ancient Persia to Greece, Rome, India, and China [1]. In Persian medicine, pomegranate was prescribed for digestive disorders and parasitic infections. Greek physicians, including Hippocrates, recommended pomegranate for inflammatory conditions and wound healing. Traditional Chinese Medicine employed pomegranate peel for its astringent and antimicrobial properties, while Ayurvedic practitioners utilized various parts of the plant to treat diabetes, diarrhea, and cardiovascular ailments [1].










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